Instituto Nacional de Investigação Agrária e Veterinária, I.P.
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18
NEOVAC


Designação do projeto | NEOVAC - Development of an experimental vaccine against neosporosis in cattle
Código do projeto | POCI-01-0145-FEDER-031020
Objetivo principal | OT 1 Reforçar a investigação, o desenvolvimento tecnológico e a inovação.
Região de intervenção | 83,95% Norte; 16,05% Alentejo
Entidade beneficiária | Instituto Biologia Molecular e Celular - IBMC; Universidade do Porto; Instituto Nacional de Investigação Agrária e Veterinária, I.P. (INIAV, I.P.) 
Data da aprovação | 28/02/2018 
Data de início | 01/06/2018 
Data de conclusão | 31/05/2021 
Custo total elegível | 239.804,80€; Custo elegível INIAV| 38.500,00€
Apoio financeiro total da União Europeia | FEDER – 203.834,08€ (INIAV-32.725,00€)
Apoio OE| 35.970,72€ (INIAV – 5.775,00€)


Objetivos, atividades e resultados esperados

Objetivos:
The main objective of this project is the development of a mucosal vaccine against bovine neosporosis.

Atividades:
1. Optimization of the immunogenic formulation: effect of the administration route and additional adjuvants
2. Identification of T cell populations involved in memory and protection conferred by immunization
3. Assessment of the protective effect of B-cells and mucosal produced antibodies in vaccinated mice
4. Characterization of the parasite-specific immune response induced by immunization in cattle
5. Immunoreactive profiling of immunizing antigens
6. Assessment of the protective effect of mucosal immunization in cattle

Resultados esperados:
The expected outcome of the project is to achieve an immunization procedure that could effectively vaccinate cattle against neosporosis, thus reducing parasite prevalence and overall transmission.


Cofinanciado por:





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